SCHEMBL267205

SCHEMBL267205

O=C(O)Cc1ccc(C(F)(F)F)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 9/20 0.68
RXRG P48443 9/20 0.68
RXRB P28702 8/20 0.68
PSEN1 P49768 1/20 0.67
PSEN2 P49810 1/20 0.67
APH1B Q8WW43 1/20 0.67
NCSTN Q92542 1/20 0.67
APH1A Q96BI3 1/20 0.67
PSENEN Q9NZ42 1/20 0.67
CA2 P00918 1/20 0.56
CAMK2A Q9UQM7 1/20 0.56
CYP2C9 P11712 1/20 0.55
PIK3CA P42336 1/20 0.54
HDAC1 Q13547 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
AKR1B1 P15121 1/20 0.54
SRD5A2 P31213 1/20 0.53
ABCC4 O15439 1/20 0.52
LMNA P02545 1/20 0.52
GAA P10253 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28015733 0.98 RXRA (0.66) RXRARXRGRXRBPSEN1PSEN2
Hydrochloric Acid SCHEMBL2528774 0.98 RXRA (0.66) RXRARXRGRXRBPSEN1PSEN2
SCHEMBL2272003 0.94 RXRA (0.77) RXRARXRGRXRBPSEN1PSEN2
SCHEMBL8329343 0.89 LTA4H (0.60) RXRARXRGRXRBPSEN1PSEN2
SCHEMBL5464443 0.89 RXRA (0.57) RXRARXRGRXRBPSEN1PSEN2
Trifluoromethylbenzene SCHEMBL27770931 0.88 AKR1B1 (0.68) RXRARXRGRXRBPSEN1PSEN2
Toluene SCHEMBL28209101 0.88 RXRA (0.55) RXRARXRGRXRBPSEN1PSEN2
SCHEMBL30567612 0.87 PSEN1 (0.58) RXRARXRGRXRBPSEN1PSEN2
SCHEMBL28287532 0.86 RXRA (0.54) RXRARXRGRXRBPSEN1PSEN2
SCHEMBL3498978 0.85 MAOB (0.67) RXRARXRGRXRBFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1453 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-119430210-A Preparation method of hydrophobic synthetic mica 河南晶多多新材料科技有限公司 2025-02-14 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-117361931-B Anticorrosive concrete additive and preparation method thereof 邢台建工商品混凝土有限公司 2024-02-09 CN claimed
CN-117361931-A Anticorrosive concrete additive and preparation method thereof 邢台建工商品混凝土有限公司 2024-01-09 CN claimed
CN-117143097-A Beta-carbopol compound, preparation method thereof and application of beta-carbopol compound in resisting Alzheimer disease 中国人民解放军北部战区总医院 2023-12-01 CN claimed
CN-115215879-B 3-aryl-4, 5-pyranocoumarin derivative, and preparation method and application thereof 广西中医药大学 2023-10-20 CN claimed
CN-116836081-A Ether epoxy toughening agent and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-10-03 CN claimed
CN-116082720-B High-strength super-wear-resistant rubber conveyer belt and production method thereof 河北九洲橡胶科技股份有限公司 2023-06-09 CN claimed
WO-1997027331-A2 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES RAPIGENE, INC. (US) 1997-07-31 WO claimed
US-5631038-A COMPOUNDS (TASTANDS) TO REDUCE OR ELIMINATE A BITTER OR METALLIC TASTE ARE ADDED TO FOODS CONTAINING SODIUM CHLORIDE BIORESEARCH, INC. (US) 1997-05-20 US claimed
US-5631294-A PHENOXY- OR PHENYL-ALKANOIC ACIDS BIORESEARCH, INC. (US) 1997-05-20 US claimed
EP-0727151-A2 Ingestibles containing substantially tasteless sweetness inhibitors as bitter taste reducers or substantially tasteless bitter inhibitors as sweet taste reducers BIORESEARCH, INC. (US) 1996-08-21 EP claimed
EP-0661932-A4 SPECIFIC EATABLE TASTE MODIFIERS. BIORESEARCH INC (US) 1996-06-05 EP claimed
EP-0661932-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1995-07-12 EP claimed
EP-0585296-A1 2-(PYRROLIDINYL-1-METHYL)-PIPERIDINE DERIVATIVES AND THEIR USE AS KAPPA-RECEPT OR AGONISTS Smithkline Beecham Farmaceutici S.p.A. (IT) 1994-03-09 EP claimed
WO-1993010677-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1993-06-10 WO claimed
WO-1992020657-A1 2-(PYRROLIDINYL-1-METHYL)-PIPERIDINE DERIVATIVES AND THEIR USE AS KAPPA-RECEPT OR AGONISTS SMITHKLINE BEECHAM FARMACEUTICI S.P.A. (IT) 1992-11-26 WO claimed
WO-1991018523-A1 INGESTIBLES CONTAINING SUBSTANTIALLY TASTELESS SWEETNESS INHIBITORS AS BITTER TASTE REDUCERS OR SUBSTANTIALLY TASTELESS BITTER INHIBITORS AS SWEET TASTE REDUCERS BIORESEARCH, INC. (US) 1991-12-12 WO claimed