Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30584166 | 0.81 | CHRNB4 (0.42) | CHRNB4CHRNA3CHRM4CHRM5CHRM1 | |
| SCHEMBL27669020 | 0.81 | CHRNB4 (0.42) | CHRNB4CHRNA3CHRM4CHRM5CHRM1 | |
| SCHEMBL2098632 | 0.77 | CHRM4 (0.45) | CHRNB4CHRNA3CHRM4CHRM5CHRM1 | |
| SCHEMBL16757410 | 0.75 | CYP1A2 (0.42) | CHRNB4CHRNA3 | |
| SCHEMBL16757394 | 0.74 | CHRNB4 (0.41) | CHRNB4CHRNA3CHRM4CHRM5CHRM1 | |
| SCHEMBL28022336 | 0.74 | GPR119 (0.36) | HRH3HSD17B10 | |
| SCHEMBL3453171 | 0.73 | PREP (0.41) | HRH3HPGDEPHX1HSD17B10 | |
| SCHEMBL6262157 | 0.72 | MEN1 (0.40) | CHRNB4CHRNA3CHRM4CHRM5CHRM1 | |
| SCHEMBL14061760 | 0.72 | MEN1 (0.40) | CHRNB4CHRNA3CHRM4CHRM5CHRM1 | |
| SCHEMBL11483634 | 0.72 | ALDH1A1 (0.44) | CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109562111-A | CK2 inhibitor, its composition and method | 北极星药业股份有限公司 | 2019-04-02 | — | — | CN | disclosed |