Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 6/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.35 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL211910 | 0.83 | KCNH2 (0.46) | KDM5CKDM4CNMT1KCNH2OPRD1 | |
| Tert-Butyl Formate SCHEMBL27666302 | 0.79 | ALDH1A1 (0.50) | KDM5CKDM4CCXCR4 | |
| Tert-Butyl Formate SCHEMBL28289066 | 0.78 | KDM5C (0.43) | KDM5CKDM4CCXCR4SCN9ASRPK1 | |
| Tert-Butyl Formate SCHEMBL27993861 | 0.77 | KDM5C (0.38) | KDM5CKDM4COPRD1CXCR4 | |
| Tert-Butyl Formate SCHEMBL27934401 | 0.76 | KDM5C (0.50) | KDM5CKDM4COPRD1CXCR4 | |
| Tert-Butyl Formate SCHEMBL28290435 | 0.76 | ALDH1A1 (0.38) | NMT1KCNH2OPRD1JAK2JAK1 | |
| Tert-Butyl Formate SCHEMBL28872040 | 0.76 | ALOX15 (0.53) | — | |
| Tert-Butyl Formate SCHEMBL27844700 | 0.74 | HPGD (0.51) | CXCR4 | |
| Tert-Butyl Formate SCHEMBL28305079 | 0.74 | KDM5C (0.39) | KDM5CKDM4COPRD1CXCR4SCN9A | |
| Tert-Butyl Formate SCHEMBL27524789 | 0.74 | SIGMAR1 (0.66) | CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563092-A | It can be used as the 2- phenylimidazole of the active inhibitor of mammal tyrosine kinase ROR1 simultaneously [4,5-B] pyridine -7- amine derivative | 坎塞拉有限公司 | 2019-04-02 | — | — | CN | disclosed |