Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207529 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SLC6A4SLC6A2JAK2JAK1 | |
| Tert-Butyl Formate SCHEMBL28289206 | 0.79 | SIGMAR1 (0.42) | SLC6A4SIGMAR1OPRD1CYP1A2CHRM2 | |
| Tert-Butyl Formate SCHEMBL27844700 | 0.77 | HPGD (0.51) | ALDH1A1SIGMAR1CYP1A2CHRM2 | |
| Tert-Butyl Formate SCHEMBL28289066 | 0.76 | KDM5C (0.43) | ALDH1A1SRPK1SIGMAR1 | |
| Tert-Butyl Formate SCHEMBL27844848 | 0.76 | CHRNB2 (0.52) | ALDH1A1SIGMAR1 | |
| Tert-Butyl Formate SCHEMBL28872040 | 0.76 | ALOX15 (0.53) | ALDH1A1SLC6A4SLC6A2CYP1A2 | |
| Tert-Butyl Formate SCHEMBL28289062 | 0.76 | KDM5C (0.38) | JAK2JAK1JAK3NMT1SRPK1 | |
| Tert-Butyl Formate SCHEMBL28305079 | 0.74 | KDM5C (0.39) | ALDH1A1SLC6A4SIGMAR1TLR9TLR8 | |
| Tert-Butyl Formate SCHEMBL27524789 | 0.74 | SIGMAR1 (0.66) | ALDH1A1SIGMAR1CHRM2LMNA | |
| Tert-Butyl Formate SCHEMBL27993846 | 0.73 | CXCR4 (0.48) | ALDH1A1SIGMAR1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563092-A | It can be used as the 2- phenylimidazole of the active inhibitor of mammal tyrosine kinase ROR1 simultaneously [4,5-B] pyridine -7- amine derivative | 坎塞拉有限公司 | 2019-04-02 | — | — | CN | disclosed |