Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.40 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4980425 | 0.79 | TEAD1 (0.56) | NFE2L2TEAD1TEAD3 | |
| SCHEMBL28041177 | 0.79 | PARP15 (0.50) | — | |
| SCHEMBL525095 | 0.78 | CYP2D6 (0.56) | LTA4HCYP3A4CYP2D6HPGD | |
| SCHEMBL16838748 | 0.76 | NFE2L2 (0.56) | NFE2L2 | |
| SCHEMBL1697752 | 0.76 | NFE2L2 (0.56) | NFE2L2LTA4HHPGD | |
| SCHEMBL13724833 | 0.76 | NFE2L2 (0.56) | NFE2L2HPGD | |
| SCHEMBL833958 | 0.76 | NFE2L2 (0.51) | NFE2L2TEAD1TEAD3MCHR1HPGD | |
| SCHEMBL2562093 | 0.76 | NFE2L2 (0.83) | NFE2L2LTA4HMCHR1HPGD | |
| SCHEMBL12743776 | 0.75 | CYP2D6 (0.59) | LTA4HCYP3A4CYP2D6HPGD | |
| SCHEMBL17303639 | 0.74 | LNPEP (0.50) | LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458902-B | Pyridine derivate | 安斯泰来制药株式会社 | 2019-04-05 | — | — | CN | disclosed |