Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28289353 | 0.92 | SGMS2 (0.44) | SGMS2MEN1KMT2AALDH1A1LRRK2 | |
| SCHEMBL15534323 | 0.86 | EGFR (0.47) | SGMS2MEN1KMT2AALDH1A1LRRK2 | |
| SCHEMBL28289352 | 0.82 | RAB9A (0.53) | KMT2AALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL10246040 | 0.78 | EGFR (0.45) | SGMS2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL28289347 | 0.77 | SGMS2 (0.48) | SGMS2MEN1KMT2AALDH1A1LRRK2 | |
| SCHEMBL22090555 | 0.75 | ALDH1A1 (0.63) | KMT2AALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL20401137 | 0.75 | EGFR (0.43) | SGMS2MEN1KMT2AALDH1A1LRRK2 | |
| SCHEMBL20400394 | 0.74 | SGMS2 (0.41) | SGMS2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL20401050 | 0.73 | CA1 (0.44) | SGMS2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10246338 | 0.72 | STAT3 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003104-A | Salicyclic acid derivatives, its pharmaceutically acceptable salt, its composition and its application method | 多伦多大学管理委员会 | 2019-07-12 | — | — | CN | disclosed |
| CN-105120854-B | Novel salicylic acid derivatives, pharmaceutically acceptable salts thereof, compositions thereof, and methods of use thereof | 多伦多大学管理委员会 | 2019-04-09 | — | — | CN | disclosed |