SCHEMBL28289641

SCHEMBL28289641

Cc1cccc(C(C)(c2ccccc2)C(C)(C)C)c1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.39
ATM Q13315 1/20 0.39
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
KIF11 P52732 1/20 0.36
MAPK1 P28482 1/20 0.34
ESR1 P03372 3/20 0.34
ESR2 Q92731 3/20 0.34
KCNN4 O15554 4/20 0.33
TSHR P16473 1/20 0.33
ACHE P22303 1/20 0.33
ALDH1A1 P00352 3/20 0.32
TAAR1 Q96RJ0 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP3A4 P08684 2/20 0.31
KMT2A Q03164 2/20 0.31
CYP1A2 P05177 2/20 0.31
MEN1 O00255 1/20 0.31
AKR1B10 O60218 1/20 0.31
ABCB11 O95342 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10576781 0.86 MAPK1 (0.38) GABRA1GABRB2KIF11MAPK1ESR1
SCHEMBL3740131 0.80 ESR1 (0.42) TRPA1ATMGABRA1GABRB2KIF11
SCHEMBL5598485 0.80 ESR1 (0.44) TRPA1ATMGABRA1GABRB2KIF11
SCHEMBL18957950 0.78 TRPA1 (0.43) TRPA1ATMGABRA1GABRB2TSHR
SCHEMBL8853833 0.77 TRPA1 (0.39) TRPA1ATMGABRA1GABRB2KIF11
SCHEMBL1618598 0.77 KCNN4 (0.43) TRPA1ATMGABRA1GABRB2KIF11
SCHEMBL4615965 0.76 KCNN4 (0.46) TRPA1ATMGABRA1GABRB2KIF11
SCHEMBL11524886 0.76 TRPA1 (0.41) TRPA1ATMGABRA1GABRB2KIF11
Iodide SCHEMBL1618290 0.76 KCNN4 (0.41) TRPA1ATMGABRA1GABRB2KIF11
Ammonia Solution, Strong SCHEMBL27910256 0.76 TRPA1 (0.42) TRPA1ATMGABRA1GABRB2KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117138384-A Acid anhydride production process and device 濮阳市恒丰电子绝缘材料有限公司 2023-12-01 CN disclosed
CN-109666032-B Preparation method of pyromellitic anhydride 沾化大荣化工科技有限公司 2020-07-07 CN disclosed
CN-109666032-A A kind of preparation method of pyromellitic dianhydride 沾化大荣化工科技有限公司 2019-04-23 CN disclosed