Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 4/20 | 0.50 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.47 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.47 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.47 |
| ▸ | FABP3 | P05413 | 4/20 | 0.46 |
| ▸ | FABP4 | P15090 | 4/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28588381 | 0.85 | PTPN1 (0.49) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL28583437 | 0.83 | KDM4A (0.41) | DHODHKDM4EHNF4AALDH1A1TP53 | |
| SCHEMBL28575871 | 0.82 | KDM4E (0.49) | FABP3FABP4DHODHKDM4EALDH1A1 | |
| SCHEMBL28588384 | 0.78 | ALDH1A1 (0.43) | FABP4DHODHKDM4EALDH1A1TP53 | |
| SCHEMBL28914795 | 0.78 | CDC25B (0.48) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL1446081 | 0.78 | CYP1A2 (0.46) | MAP2FABP3FABP4KDM4EALDH1A1 | |
| SCHEMBL28288597 | 0.77 | KDM4E (0.53) | FABP3FABP4DHODHKDM4EHNF4A | |
| SCHEMBL28576792 | 0.77 | MAPT (0.53) | ALDH1A1 | |
| SCHEMBL28583832 | 0.73 | GPR35 (0.47) | DHODHKDM4EALDH1A1 | |
| SCHEMBL28680692 | 0.72 | MEN1 (0.48) | FABP3FABP4DHODHAKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109665958-B | Method for preparing polysubstituted 1-naphthoic acid compound under catalysis of ruthenium | 广州大学 | 2021-05-11 | — | — | CN | disclosed |
| CN-109665958-A | A kind of method that ruthenium catalysis prepares polysubstituted 1- naphthoic acid class compound | 广州大学 | 2019-04-23 | — | — | CN | disclosed |