Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.47 |
| ▸ | HNF4A | P41235 | 3/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28583437 | 0.85 | KDM4A (0.41) | ACMSDHNF4ADHFRMCL1DHODH | |
| SCHEMBL28289980 | 0.85 | MAP2 (0.50) | AKR1C2AKR1C1HNF4ADHODHKDM4E | |
| SCHEMBL28575871 | 0.83 | KDM4E (0.49) | DHODHKDM4EALDH1A1HPGDPIM1 | |
| SCHEMBL28588384 | 0.80 | ALDH1A1 (0.43) | DHODHKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL28914795 | 0.80 | CDC25B (0.48) | AKR1C2AKR1C3DHODHKDM4EALDH1A1 | |
| SCHEMBL28288597 | 0.79 | KDM4E (0.53) | HNF4ADHODHKDM4EALDH1A1HPGD | |
| SCHEMBL28576792 | 0.79 | MAPT (0.53) | ALDH1A1HPGDMAPTTDP1LMNA | |
| SCHEMBL28583832 | 0.75 | GPR35 (0.47) | DHODHKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL4254028 | 0.71 | PTPN1 (0.60) | PTPN1AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL27999624 | 0.71 | PTPN1 (0.78) | PTPN1AKR1C2AKR1C1AKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109665958-B | Method for preparing polysubstituted 1-naphthoic acid compound under catalysis of ruthenium | 广州大学 | 2021-05-11 | — | — | CN | disclosed |