Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27977392 | 0.78 | MEN1 (0.56) | GPR35POLBWDR5MEN1KMT2A | |
| SCHEMBL11067214 | 0.78 | POLB (0.61) | GPR35POLBWDR5MEN1KMT2A | |
| SCHEMBL21215587 | 0.77 | WDR5 (0.51) | GPR35POLBWDR5MEN1KMT2A | |
| SCHEMBL12486124 | 0.76 | MEN1 (0.57) | GPR35POLBWDR5MEN1KMT2A | |
| SCHEMBL28588381 | 0.75 | PTPN1 (0.49) | GPR35KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL28356334 | 0.74 | NR4A1 (0.60) | GPR35POLBWDR5MEN1KMT2A | |
| SCHEMBL28288597 | 0.74 | KDM4E (0.53) | WDR5KDM4EALDH1A1HPGDNR4A1 | |
| SCHEMBL28583437 | 0.73 | KDM4A (0.41) | GPR35KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28589329 | 0.73 | AKR1C2 (0.46) | ALDH1A1DHODH | |
| SCHEMBL28289980 | 0.73 | MAP2 (0.50) | KDM4EALDH1A1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109665958-B | Method for preparing polysubstituted 1-naphthoic acid compound under catalysis of ruthenium | 广州大学 | 2021-05-11 | — | — | CN | disclosed |