Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30401063 | 0.98 | MEN1 (0.44) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL30103441 | 0.82 | CA2 (0.35) | MEN1KMT2ANOS3NOS1NOS2 | |
| SCHEMBL9912814 | 0.81 | GABRR1 (0.46) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL27779653 | 0.81 | TSHR (0.40) | TSHRALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL1515383 | 0.77 | — | — | |
| SCHEMBL2079763 | 0.77 | — | — | |
| SCHEMBL14795292 | 0.77 | — | — | |
| SCHEMBL30566969 | 0.76 | TSHR (0.39) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL310765 | 0.76 | — | — | |
| Di(Hydroxyethyl)Ether SCHEMBL6571535 | 0.74 | TSHR (0.67) | TSHRMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109694362-B | 3-arylbenzofuranone propionamide compound, composition formed by same, preparation method and application thereof | 江苏裕事达新材料科技有限责任公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-109694362-A | 3- arylben-zofuranone propanamide compounds, its composition constituted and its preparation method and application | 优缔新材料科技(苏州)有限公司 | 2019-04-30 | — | — | CN | disclosed |