Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6274318 | 0.80 | DAO (0.39) | GAAMEN1POLBRAB9AKMT2A | |
| SCHEMBL5226095 | 0.76 | ALDH1A1 (0.46) | GAAMEN1POLBRAB9AKMT2A | |
| SCHEMBL5228374 | 0.75 | KMT2A (0.49) | GAAMEN1POLBRAB9AKMT2A | |
| SCHEMBL4438126 | 0.72 | DAO (0.44) | MEN1POLBRAB9AKMT2APKM | |
| SCHEMBL4553949 | 0.69 | L3MBTL3 (0.43) | POLBL3MBTL3L3MBTL1ACKR3ALDH1A1 | |
| SCHEMBL4441335 | 0.69 | CHRNA7 (0.45) | GAAMEN1POLBRAB9AKMT2A | |
| SCHEMBL4554523 | 0.68 | CHKA (0.41) | POLBRAB9AKMT2APKMPTGER1 | |
| SCHEMBL28325838 | 0.67 | TTR (0.47) | GAADRD2DRD4DRD3POLB | |
| SCHEMBL24729399 | 0.66 | SMN1; SMN2 (0.71) | GAAMEN1POLBRAB9AKMT2A | |
| SCHEMBL4432653 | 0.66 | DAO (0.41) | MEN1KMT2APKML3MBTL1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563094-A | Acyclic derivatives, their preparation method and the pharmaceutical composition containing them that new (miscellaneous) aryl replaces | 法国施维雅药厂 | 2019-04-02 | — | — | CN | disclosed |