Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 3/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28291744 | 0.74 | TNKS (0.53) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL4773013 | 0.70 | KDM4E (0.42) | PRKDCLOXL2LCKKDM4EALDH1A1 | |
| SCHEMBL4253451 | 0.69 | GPR35 (0.61) | KDM4EALDH1A1GPR35 | |
| SCHEMBL28290283 | 0.69 | GPR35 (0.47) | LOXL2KDM4EALDH1A1GPR35NPC1 | |
| SCHEMBL909747 | 0.69 | CYP1A2 (0.64) | PRKDCLCKKDM4EALDH1A1HPGD | |
| SCHEMBL3695062 | 0.68 | CYP3A4 (0.53) | PRKDCLCKKDM4EALDH1A1HPGD | |
| SCHEMBL4251645 | 0.68 | KDM4E (0.53) | KDM4EALDH1A1MAPTHSD17B10GPR35 | |
| SCHEMBL23240707 | 0.67 | ATP1A1 (0.47) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL4247291 | 0.66 | AKR1B1 (0.56) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL3696230 | 0.66 | CYP1A1 (0.67) | PRKDCLCKKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641864-A | ANTI-INFECTIVE AGENTS | 邓迪大学 | 2019-04-16 | — | — | CN | disclosed |