Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4773864 | 0.81 | HPGD (0.39) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4777597 | 0.75 | GPR35 (0.60) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28290283 | 0.72 | GPR35 (0.47) | KDM4EALDH1A1SMN1; SMN2LOXL2NPC1 | |
| SCHEMBL4253451 | 0.72 | GPR35 (0.61) | KDM4EALDH1A1GPR35 | |
| SCHEMBL3844010 | 0.72 | NPC1 (0.65) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23240707 | 0.70 | ATP1A1 (0.47) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28290280 | 0.70 | PRKDC (0.36) | KDM4EMAPTALDH1A1HPGDHTT | |
| SCHEMBL28213200 | 0.69 | KMT2A (0.58) | KDM4EMAPTALDH1A1HPGDNQO1 | |
| SCHEMBL909747 | 0.69 | CYP1A2 (0.64) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL24254913 | 0.69 | ALDH1A1 (0.55) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1897873-A1 | A process for the preparation of nitrile compounds used as intermediates in the synthesis of cysteinyl leukotrienes antagonists | Dipharma Francis S.r.l. (IT) | 2008-03-12 | — | — | EP | claimed |
| US-20080039640-A1 | PROCESS FOR THE PREPARATION OF NITRILE COMPOUNDS | DIPHARMA FRANCIS S.R.L. (IT) | 2008-02-14 | — | — | US | claimed |
| EP-1897873-A1 | A process for the preparation of nitrile compounds used as intermediates in the synthesis of cysteinyl leukotrienes antagonists | Dipharma Francis S.r.l. (IT) | 2008-03-12 | — | — | EP | disclosed |
| US-20080039640-A1 | PROCESS FOR THE PREPARATION OF NITRILE COMPOUNDS | DIPHARMA FRANCIS S.R.L. (IT) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039640-A1 | PROCESS FOR THE PREPARATION OF NITRILE COMPOUNDS | NOS1, REN, NOS2 | KDM4E 3474/4885MAPT 3497/4885ALDH1A1 811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.