Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19742671 | 0.81 | NPBWR1 (0.38) | NPBWR1MCHR1MAPTHTTALDH1A1 | |
| SCHEMBL28288993 | 0.79 | KMT2A (0.41) | NPBWR1MCHR1TDP1MAPTPOLB | |
| SCHEMBL28288991 | 0.77 | TBXA2R (0.35) | NPBWR1MCHR1TDP1MAPTPOLB | |
| SCHEMBL19753983 | 0.75 | ALOX5 (0.38) | NPBWR1MCHR1MAPTALDH1A1TAAR1 | |
| SCHEMBL30279968 | 0.72 | KMT2A (0.35) | TDP1POLBHTTALDH1A1RAB9A | |
| SCHEMBL19742509 | 0.72 | KMT2A (0.35) | TDP1POLBHTTALDH1A1RAB9A | |
| SCHEMBL29352631 | 0.72 | KMT2A (0.35) | TDP1POLBHTTALDH1A1RAB9A | |
| SCHEMBL19742711 | 0.72 | RAB9A (0.50) | TDP1MAPTPOLBHTTALDH1A1 | |
| SCHEMBL19742749 | 0.70 | TBXA2R (0.39) | NPBWR1MCHR1POLBALDH1A1TAAR1 | |
| SCHEMBL28290359 | 0.70 | ALDH1A1 (0.42) | TDP1MAPTHTTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109562111-A | CK2 inhibitor, its composition and method | 北极星药业股份有限公司 | 2019-04-02 | — | — | CN | disclosed |