Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290359 | 0.82 | ALDH1A1 (0.42) | RAB9ATSHRMAPTHTTCYP1A2 | |
| SCHEMBL30279930 | 0.78 | LMNA (0.36) | LMNAMETNPC1RAB9AHSP90AA1 | |
| SCHEMBL30279896 | 0.76 | MTNR1A (0.33) | HSP90AA1TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19742597 | 0.76 | MTNR1A (0.33) | HSP90AA1TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL25253331 | 0.74 | LMNA (0.39) | LMNAMETNPC1RAB9A | |
| SCHEMBL28681184 | 0.74 | AKR1B1 (0.39) | LMNANPC1RAB9AMAPK1TSHR | |
| SCHEMBL28290383 | 0.74 | — | — | |
| SCHEMBL19753976 | 0.73 | NQO2 (0.45) | MAPTHTT | |
| SCHEMBL30279910 | 0.72 | ALOX5 (0.31) | MAPK1MAPT | |
| SCHEMBL29223381 | 0.70 | GAA (0.50) | MAPK1TSHRGAAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109562111-A | CK2 inhibitor, its composition and method | 北极星药业股份有限公司 | 2019-04-02 | — | — | CN | disclosed |