SCHEMBL28290767

SCHEMBL28290767

CC(C)(C)OC(=O)CCn1cnc([N+](=O)[O-])c1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.44
ALDH1A1 P00352 2/20 0.41
PKM P14618 1/20 0.41
TAAR1 Q96RJ0 1/20 0.40
MITF O75030 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
MEN1 O00255 1/20 0.37
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
HIF1A Q16665 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27968562 0.85 L3MBTL1 (0.47) L3MBTL1ALDH1A1PKMTAAR1MITF
SCHEMBL28290763 0.83 MITF (0.52) L3MBTL1ALDH1A1PKMTAAR1MITF
SCHEMBL2878417 0.81 TAAR1 (0.46) L3MBTL1ALDH1A1PKMTAAR1
SCHEMBL2976254 0.80 L3MBTL1 (0.50) L3MBTL1ALDH1A1PKMTAAR1SMN1; SMN2
SCHEMBL11908229 0.80 RAB9A (0.61) ALDH1A1PKMSMN1; SMN2GAAMAPT
SCHEMBL28290762 0.79 ALDH1A1 (0.45) L3MBTL1ALDH1A1PKMTAAR1MITF
SCHEMBL28290787 0.78 ALDH1A1 (0.54) ALDH1A1PKMMITFPOLBKMT2A
SCHEMBL4412169 0.77 L3MBTL1 (0.50) L3MBTL1ALDH1A1PKMTAAR1SMN1; SMN2
SCHEMBL28401515 0.77 L3MBTL1 (0.43) L3MBTL1ALDH1A1PKMTAAR1MITF
SCHEMBL14696607 0.76 L3MBTL1 (0.53) L3MBTL1ALDH1A1PKMTAAR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109706198-A A kind of method that online enzyme process closes nitro imidazole derivatives 浙江工业大学 2019-05-03 CN disclosed