Dimethylformamide

Dimethylformamide

SCHEMBL28290916

C=CCOCc1ccccc1.CN(C)C=O

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.45
ALOX15 P16050 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ALOX5 P09917 1/20 0.38
TK1 P04183 1/20 0.37
ALDH1A1 P00352 2/20 0.37
FAAH O00519 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
TEAD3 Q99594 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
BCHE P06276 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20953940 0.86 TSHR (0.61) TSHRALOX15L3MBTL1ALOX5CA1
SCHEMBL149658 0.86 TSHR (0.61) TSHRALOX15L3MBTL1ALOX5CA1
Ammonia Solution, Strong SCHEMBL27983434 0.84 TSHR (0.58) TSHRALOX15L3MBTL1ALOX5CA1
SCHEMBL5035399 0.84 TSHR (0.58) TSHRALOX15L3MBTL1ALOX5CA1
SCHEMBL27864528 0.81 TSHR (0.50) TSHRALOX15L3MBTL1ALOX5TK1
SCHEMBL16679883 0.79 TSHR (0.52) TSHRALOX15L3MBTL1ALOX5CA1
SCHEMBL3814937 0.77 TSHR (0.54) TSHRALOX15L3MBTL1CA1CA2
SCHEMBL4778780 0.75 TSHR (0.42) TSHRALOX15L3MBTL1ALDH1A1CA1
SCHEMBL30425720 0.74 TSHR (0.61) TSHRL3MBTL1ALOX5TK1ALDH1A1
SCHEMBL76044 0.74 TSHR (0.61) TSHRL3MBTL1ALOX5TK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106572659-B Harmful arthropod agent for preventing and eliminating containing amide compound 住友化学株式会社 2019-05-10 CN disclosed