SCHEMBL149658

SCHEMBL149658

C=CCOCc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.61
ALOX15 P16050 1/20 0.49
CA1 P00915 4/20 0.46
CA2 P00918 2/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
IDO1 P14902 1/20 0.44
AGXT P21549 1/20 0.43
ALOX5 P09917 1/20 0.41
KDM4E B2RXH2 1/20 0.41
POLB P06746 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TACR1 P25103 2/20 0.40
CYP3A4 P08684 1/20 0.39
TEAD3 Q99594 1/20 0.39
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20953940 1.00 TSHR (0.61) TSHRALOX15CA1CA2CA7
Ammonia Solution, Strong SCHEMBL27983434 0.98 TSHR (0.58) TSHRALOX15CA1CA2CA7
SCHEMBL5035399 0.98 TSHR (0.58) TSHRALOX15CA1CA2CA7
SCHEMBL16679883 0.92 TSHR (0.52) TSHRALOX15CA1CA2CA7
SCHEMBL27864528 0.90 TSHR (0.50) TSHRALOX15CA1CA2CA7
SCHEMBL3814937 0.90 TSHR (0.54) TSHRALOX15CA1CA2CA7
SCHEMBL4778780 0.88 TSHR (0.42) TSHRALOX15CA1CA2CA7
Dimethylformamide SCHEMBL28290916 0.86 TSHR (0.45) TSHRALOX15CA1CA2CA7
SCHEMBL27837904 0.85 TSHR (0.54) TSHRALOX15CA1CA2CA7
SCHEMBL101220 0.85 L3MBTL1 (0.53) TSHRALOX15CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
US-12379611-B2 Diffractive contact lenses ALCON INC. (CH) 2025-08-05 US claimed
CN-119960255-A Photosensitive resin composition, resist ink, resist laminate and use thereof 杭州福斯特电子材料有限公司 2025-05-09 CN claimed
CN-119930381-A Synthesis method of Z-configuration chiral olefin 深圳连续制药科技有限公司 2025-05-06 CN claimed
US-20250129107-A1 HYDROSILYLATION PROCESS PHOTOCATALYSED BY A MANGANESE COMPLEX CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2025-04-24 US claimed
CN-119842266-A Durable antibacterial steaming-resistant ink as well as preparation method and application thereof 江苏博来特新材料有限公司 2025-04-18 CN claimed
CN-119798564-A Photopolymer holographic recording medium, grating, preparation method and equipment thereof 珠海莫界科技有限公司 2025-04-11 CN claimed
CN-119505069-A Acrylic resin and preparation method thereof 湖北雨田科技有限公司 2025-02-25 CN claimed
CN-119343356-A Hydrosilylation process by manganese complex photocatalysis 埃肯有机硅法国简易股份公司 2025-01-21 CN claimed
CN-119208536-A Negative electrode plate, preparation method of negative electrode plate and battery 荣耀终端有限公司 2024-12-27 CN claimed
EP-0544233-A1 Fluorine-containing copolymer useful as paint vehicle CENTRAL GLASS COMPANY, LIMITED (JP) 1993-06-02 EP claimed
EP-0152801-B1 PROCESS FOR MANUFACTURING BENZALDEHYDE DIALKYLACETALS BASF Aktiengesellschaft (DE) 1987-05-27 EP claimed
EP-0191208-A1 Production of bis(alpha-alkylbenzyl)ethers ATLANTIC RICHFIELD COMPANY (US) 1986-08-20 EP claimed
EP-0152801-A2 Process for manufacturing benzaldehyde dialkylacetals BASF Aktiengesellschaft (DE) 1985-08-28 EP claimed
US-4528406-A Production of bis(alpha-alkylbenzyl)ethers ATLANTIC RICHFIELD COMPANY (US) 1985-07-09 US claimed
US-4521636-A CONDENSATION OF ALPHA ALKYLBENZYL ALCOHOL IN PRESENCE OF ALUMINUM SULFATE CATALYST ATLANTIC RICHFIELD COMPANY (US) 1985-06-04 US claimed
US-4521637-A ETHERIFICATION OF ALPHA-ALKYLBENZYL ALCOHOL USING ACID TREATED ALUMINA CATALYST ATLANTIC RICHFIELD COMPANY (US) 1985-06-04 US claimed
US-4521635-A USING ACID-TREATED ALUMINA CATALYST ATLANTIC RICHFIELD COMPANY (US) 1985-06-04 US claimed
EP-0054699-B1 METHOD FOR THE CATALYTIC HYDROGENOLYSIS OF PARA-SUBSTITUTED BENZALDEHYDE-DIMETHYL ACETALS INTO THE CORRESPONDING BENZYLMETHYL ETHERS HOECHST AKTIENGESELLSCHAFT (DE) 1984-03-14 EP claimed
US-4413149-A COBALT CARBONYL AND A NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HOECHST AKTIENGESELLSCHAFT (DE) 1983-11-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES LBR, CRYZ, CRYAA TSHR 1437/4885ALOX15 3479/4885CA1 774/4885
US-20250129107-A1 HYDROSILYLATION PROCESS PHOTOCATALYSED BY A MANGANESE COMPLEX C9, PIEZO1, HMOX1 TSHR 4717/4885ALOX15 45/4885CA1 488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.