SCHEMBL3814937

SCHEMBL3814937

C=CCOCCOCc1ccccc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.54
NAAA Q02083 1/20 0.46
ALOX15 P16050 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
TEAD3 Q99594 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
MAPT P10636 1/20 0.41
LTA4H P09960 1/20 0.40
IDO1 P14902 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
AGXT P21549 1/20 0.39
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HRH4 Q9H3N8 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL101220 0.91 L3MBTL1 (0.53) TSHRNAAAALOX15L3MBTL1TEAD3
SCHEMBL149658 0.90 TSHR (0.61) TSHRALOX15L3MBTL1TEAD3CA1
SCHEMBL20953940 0.90 TSHR (0.61) TSHRALOX15L3MBTL1TEAD3CA1
SCHEMBL5035399 0.88 TSHR (0.58) TSHRALOX15L3MBTL1TEAD3CA1
Ammonia Solution, Strong SCHEMBL27983434 0.88 TSHR (0.58) TSHRALOX15L3MBTL1TEAD3CA1
Adipic Acid SCHEMBL4790742 0.86 L3MBTL1 (0.47) TSHRL3MBTL1TEAD3MAPTHTT
SCHEMBL11103994 0.85 TSHR (0.47) TSHRNAAAALOX15L3MBTL1TEAD3
Adipic Acid SCHEMBL17022706 0.84 L3MBTL1 (0.46) L3MBTL1TEAD3MAPTHTTSMN1; SMN2
SCHEMBL321275 0.83 LMNA (0.51) L3MBTL1MAPTLTA4HSMN1; SMN2KDM4E
SCHEMBL1991359 0.82 TSHR (0.78) TSHRNAAAL3MBTL1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798564-A Photopolymer holographic recording medium, grating, preparation method and equipment thereof 珠海莫界科技有限公司 2025-04-11 CN claimed
CN-119798564-A Photopolymer holographic recording medium, grating, preparation method and equipment thereof 珠海莫界科技有限公司 2025-04-11 CN disclosed
WO-2024249235-A1 ANTI-HUMAN CD33 BET DEGRADER ANTIBODY-DRUG CONJUGATES ABBVIE INC. (US) 2024-12-05 WO disclosed
CN-108976278-B Chimeric molecule and preparation and application thereof 海创药业股份有限公司 2021-04-06 CN disclosed
EP-1756135-B1 ESTER LINKED MACROLIDES USEFUL FOR THE TREATMENT OF MICROBIAL INFECTIONS GLAXOSMITHKLINE ZAGREB (HR) 2009-08-12 EP disclosed
EP-1756135-B1 ESTER LINKED MACROLIDES USEFUL FOR THE TREATMENT OF MICROBIAL INFECTIONS GLAXOSMITHKLINE ZAGREB (HR) 2009-08-12 EP disclosed
US-20080255060-A1 Ester Linked Macrolides Useful For The Treatment of Microbial Infections GLAXOSMITHKLINE ISTRAZIVACKI CENTER ZAGREB (HR) 2008-10-16 US disclosed
CN-101068824-A Ester-linked macrolides for the treatment of microbial infections GLAXOSMITHKLINE ZAGREB (HR) 2007-11-07 CN disclosed
EP-1756135-A1 ESTER LINKED MACROLIDES USEFUL FOR THE TREATMENT OF MICROBIAL INFECTIONS GlaxoSmithKline istrazivacki centar Zagreb d.o.o. (HR) 2007-02-28 EP disclosed
WO-2005108412-A1 ESTER LINKED MACROLIDES USEFUL FOR THE TREATMENT OF MICROBIAL INFECTIONS GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (US) 2005-11-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080255060-A1 Ester Linked Macrolides Useful For The Treatment of Microbial Infections CYP51A1, TLR5, MALT1 TSHR 2881/4885NAAA 842/4885ALOX15 130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.