SCHEMBL4778780

SCHEMBL4778780

C=CCOCc1ccc(COCC=C)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
ALOX15 P16050 2/20 0.37
ALDH1A1 P00352 5/20 0.37
CYP3A4 P08684 2/20 0.37
TP53 P04637 1/20 0.37
ALOX12 P18054 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA9 Q16790 2/20 0.33
PPARG P37231 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
CA7 P43166 2/20 0.32
XDH P47989 1/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
KMT2A Q03164 1/20 0.32
IDO1 P14902 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16949959 0.91 TSHR (0.36) TSHRALOX15ALDH1A1CYP3A4TP53
SCHEMBL7307672 0.91 IDO1 (0.46) TSHRALDH1A1TP53CA2XDH
SCHEMBL13370317 0.89 TSHR (0.41) TSHRALOX15ALDH1A1CYP3A4SMN1; SMN2
SCHEMBL8758520 0.89 ALDH1A1 (0.46) TSHRALOX15ALDH1A1CYP3A4TP53
SCHEMBL9095391 0.89 AGXT (0.48) TSHRALOX15ALDH1A1CYP3A4TP53
SCHEMBL4591314 0.89 IDO1 (0.48) TSHRALDH1A1CYP3A4SMN1; SMN2MEN1
SCHEMBL149658 0.88 TSHR (0.61) TSHRALOX15CYP3A4CA1CA2
SCHEMBL20953940 0.88 TSHR (0.61) TSHRALOX15CYP3A4CA1CA2
SCHEMBL5035399 0.86 TSHR (0.58) TSHRALOX15CYP3A4CA1CA2
SCHEMBL8730874 0.85 ALDH1A1 (0.46) TSHRALOX15ALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1973989-A2 FLAME RETARDANT RESIN COMPOSITION GENERAL ELECTRIC COMPANY (US) 2008-10-01 EP claimed
WO-2007084664-A2 FLAME RETARDANT RESIN COMPOSITION GENERAL ELECTRIC COMPANY (US) 2007-07-26 WO claimed
US-20070173572-A1 Flame retardant resin composition GENERAL ELECTRIC COMPANY 2007-07-26 US claimed
EP-3572464-B1 COMPOSITION FOR LAMINATE OSAKA SODA CO LTD (JP) 2025-06-04 EP disclosed
US-11773207-B2 Thiol compound, method for synthesizing same, and uses for said thiol compound SHIKOKU CHEMICALS CORPORATION (JP) 2023-10-03 US disclosed
US-11761121-B2 Method for producing polyacetal fiber MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-09-19 US disclosed
WO-2023047901-A1 NON-PHOTOSENSITIVE INSULATION FILM-FORMING COMPOSITION 日産化学株式会社 2023-03-30 WO disclosed
US-11441242-B2 Method for manufacturing polyacetal fiber MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2022-09-13 US disclosed
CN-110023406-B Composition for laminate 株式会社大阪曹达 2022-09-09 CN disclosed
EP-4050134-A1 POLYACETAL FIBERS, METHOD FOR PRODUCING SAME AND MATERIAL FOR DRAWING MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2022-08-31 EP disclosed
CN-113557327-B Polyacetal fiber, method for producing same, and material for drawing 三菱瓦斯化学株式会社 2022-06-28 CN disclosed
US-20150203635-A1 SILICONE RUBBER CRESTLINE DIRECT FINANCE, L.P. 2015-07-23 US disclosed
US-20150094420-A1 FILM-FORMING COMPOSITION AND EMBEDDING MATERIAL NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-04-02 US disclosed
WO-2014004146-A1 SILICONE RUBBER EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-01-03 WO disclosed
EP-1973989-A2 FLAME RETARDANT RESIN COMPOSITION GENERAL ELECTRIC COMPANY (US) 2008-10-01 EP disclosed
WO-2007084664-A2 FLAME RETARDANT RESIN COMPOSITION GENERAL ELECTRIC COMPANY (US) 2007-07-26 WO disclosed
US-20070173572-A1 Flame retardant resin composition GENERAL ELECTRIC COMPANY 2007-07-26 US disclosed
US-20070173572-A1 Flame retardant resin composition GENERAL ELECTRIC COMPANY 2007-07-26 US disclosed
US-20070173572-A1 Flame retardant resin composition GENERAL ELECTRIC COMPANY 2007-07-26 US disclosed
US-4031163-A CROSS LINKING SELF-EXTINGUISHING, THERMAL STABILITY DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150203635-A1 SILICONE RUBBER RAD54L, DHCR24, RAD51 TSHR 3457/4885ALOX15 273/4885ALDH1A1 174/4885
US-11773207-B2 Thiol compound, method for synthesizing same, and uses for said thiol compound TST, TMT1A, CTH TSHR 3486/4885ALOX15 133/4885ALDH1A1 412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.