SCHEMBL5035399

SCHEMBL5035399

C=CCOCc1ccccc1.[NaH]

nearest known ligand 0.96

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.58
ALOX15 P16050 1/20 0.47
CA1 P00915 4/20 0.44
CA2 P00918 2/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44
IDO1 P14902 1/20 0.43
AGXT P21549 1/20 0.41
ALOX5 P09917 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 1/20 0.40
POLB P06746 1/20 0.40
TACR1 P25103 2/20 0.39
CYP3A4 P08684 1/20 0.38
TEAD3 Q99594 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20953940 0.98 TSHR (0.61) TSHRALOX15CA1CA2CA7
SCHEMBL149658 0.98 TSHR (0.61) TSHRALOX15CA1CA2CA7
Ammonia Solution, Strong SCHEMBL27983434 0.96 TSHR (0.58) TSHRALOX15CA1CA2CA7
SCHEMBL16679883 0.90 TSHR (0.52) TSHRALOX15CA1CA2CA7
SCHEMBL27864528 0.88 TSHR (0.50) TSHRALOX15CA1CA2CA7
SCHEMBL3814937 0.88 TSHR (0.54) TSHRALOX15CA1CA2CA7
SCHEMBL4778780 0.86 TSHR (0.42) TSHRALOX15CA1CA2CA7
Dimethylformamide SCHEMBL28290916 0.84 TSHR (0.45) TSHRALOX15CA1CA2CA7
SCHEMBL27837904 0.83 TSHR (0.54) TSHRALOX15CA1CA2CA7
SCHEMBL6381569 0.83 MEN1 (0.44) TSHRALOX15CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3302586-A1 ARTICLE OF COMMERCE CONTAINING ABSORBENT ARTICLE The Procter and Gamble Company (US) 2018-04-11 EP disclosed
WO-2016200716-A1 ARTICLE OF COMMERCE CONTAINING ABSORBENT ARTICLE THE PROCTER & GAMBLE COMPANY (US) 2016-12-15 WO disclosed
EP-1725643-B1 METHODS OF TREATING SURFACES USING SURFACE-TREATING COMPOSITIONS CONTAINING SULFONATED/CARBOXYLATED POLYMERS PROCTER & GAMBLE (US) 2008-07-02 EP disclosed
EP-1725642-B1 SURFACE-TREATING COMPOSITIONS CONTAINING SULFONATED/CARBOXYLATED POLYMERS PROCTER & GAMBLE (US) 2008-05-14 EP disclosed
EP-1725643-A1 METHODS OF TREATING SURFACES USING SURFACE-TREATING COMPOSITIONS CONTAINING SULFONATED/CARBOXYLATED POLYMERS The Procter and Gamble Company (US) 2006-11-29 EP disclosed
EP-1725642-A1 SURFACE-TREATING COMPOSITIONS CONTAINING SULFONATED/CARBOXYLATED POLYMERS The Procter and Gamble Company (US) 2006-11-29 EP disclosed
WO-2005090540-A1 SURFACE-TREATING COMPOSITIONS CONTAINING SULFONATED/CARBOXYLATED POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2005-09-29 WO disclosed
WO-2005090541-A1 METHODS OF TREATING SURFACES USING SURFACE-TREATING COMPOSITIONS CONTAINING SULFONATED/CARBOXYLATED POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2005-09-29 WO disclosed
US-20050202996-A1 Surface-treating compositions containing sulfonated/carboxylated polymers THE PROCTER & GAMBLE COMPANY (US) 2005-09-15 US disclosed
US-20050202995-A1 Methods of treating surfaces using surface-treating compositions containing sulfonated/carboxylated polymers THE PROCTER & GAMBLE COMPANY (US) 2005-09-15 US disclosed