Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146386 | 0.83 | PRNP (0.50) | CES2CES1BCHEPRNPALB | |
| SCHEMBL29570698 | 0.83 | PRNP (0.50) | CES2CES1BCHEPRNPALB | |
| SCHEMBL29875252 | 0.79 | PRNP (0.42) | PRNPPOLBCYP2C19MEN1KMT2A | |
| SCHEMBL9217406 | 0.79 | CES2 (0.43) | CES2CES1BCHEPRNPALB | |
| SCHEMBL11135091 | 0.79 | CES2 (0.43) | CES2CES1BCHEPRNPALB | |
| SCHEMBL31058978 | 0.79 | MEN1 (0.47) | PRNPPOLBCYP2C19MEN1KMT2A | |
| SCHEMBL5349768 | 0.79 | MEN1 (0.47) | PRNPPOLBCYP2C19MEN1KMT2A | |
| SCHEMBL30708219 | 0.78 | CES2 (0.44) | CES2CES1BCHEPRNPALDH1A1 | |
| SCHEMBL145431 | 0.78 | DGAT1 (0.46) | CES2CES1BCHEALDH1A1LMNA | |
| SCHEMBL31184721 | 0.78 | ALDH1A1 (0.52) | CES2CES1BCHEPRNPALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109627248-A | The method of level-one amine guiding building 6- (the bromo- 2- fluorophenyl of 4-) indoles simultaneously [1,2-a] quinoxaline | 桂林理工大学 | 2019-04-16 | — | — | CN | claimed |
| CN-109627248-A | The method of level-one amine guiding building 6- (the bromo- 2- fluorophenyl of 4-) indoles simultaneously [1,2-a] quinoxaline | 桂林理工大学 | 2019-04-16 | — | — | CN | disclosed |
| CN-109627248-A | The method of level-one amine guiding building 6- (the bromo- 2- fluorophenyl of 4-) indoles simultaneously [1,2-a] quinoxaline | 桂林理工大学 | 2019-04-16 | — | — | CN | disclosed |