Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1603755 | 0.84 | TSHR (0.62) | ALDH1A1SMN1; SMN2KDM4EMAPTTSHR | |
| SCHEMBL28096890 | 0.82 | MAPT (0.47) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL11201873 | 0.80 | MEN1 (0.50) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL10960395 | 0.80 | ACHE (0.61) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL10962426 | 0.80 | CA12 (0.61) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL1947858 | 0.79 | MAPK1 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL23924761 | 0.79 | FGFR1 (0.53) | ALDH1A1SMN1; SMN2KDM4ETSHRTDP1 | |
| SCHEMBL28339401 | 0.79 | FGFR1 (0.53) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| Methyl Alcohol SCHEMBL28799088 | 0.78 | CA2 (0.52) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL29419589 | 0.78 | CA2 (0.56) | ALDH1A1SMN1; SMN2KDM4EMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238131-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - Portela & Ca., S.A. (PT) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009084970-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL-PORTELA & COMPANHIA, S.A. (PT) | 2009-07-09 | — | — | WO | disclosed |