Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27645043 | 0.85 | TSHR (0.62) | MEN1KMT2ATTRALDH1A1AMY1A | |
| SCHEMBL29177230 | 0.84 | SLC6A2 (0.49) | MEN1KMT2ATTRLMNATRPV4 | |
| SCHEMBL31141912 | 0.81 | KMT2A (0.45) | MEN1KMT2ATTRLMNATRPV4 | |
| SCHEMBL10960395 | 0.81 | ACHE (0.61) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL10962426 | 0.81 | CA12 (0.61) | MEN1KMT2ALMNAALDH1A1MAPT | |
| Acetic Acid SCHEMBL10997206 | 0.81 | TTR (0.55) | MEN1KMT2ATTRLMNATRPV4 | |
| SCHEMBL2829108 | 0.80 | ALDH1A1 (0.44) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL4822633 | 0.80 | LMNA (0.46) | MEN1KMT2ATTRLMNATRPV4 | |
| SCHEMBL2127233 | 0.80 | TRPV4 (0.55) | MEN1KMT2ATTRLMNATRPV4 | |
| SCHEMBL29636402 | 0.80 | TRPV4 (0.55) | MEN1KMT2ATTRLMNATRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4376731-A | 2-NITRILES THEREOF | BOEHRINGER MANNHEIM GMBH (DE) | 1983-03-15 | — | — | US | disclosed |