Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.56 |
| ▸ | KLK7 | P49862 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL785870 | 0.85 | CTSS (0.56) | KLK5KLK7L3MBTL1SCN9ACTSS | |
| SCHEMBL16011173 | 0.80 | KLK5 (0.57) | KLK5KLK7L3MBTL1SCN9ACTSS | |
| SCHEMBL19716705 | 0.80 | KLK5 (0.57) | KLK5KLK7L3MBTL1SCN9ACTSS | |
| SCHEMBL27797344 | 0.79 | KMT2A (0.43) | L3MBTL1CTSSCTSKKMT2A | |
| SCHEMBL28291334 | 0.78 | ALDH1A1 (0.51) | L3MBTL1MEN1KMT2A | |
| SCHEMBL4416692 | 0.77 | KLK5 (0.64) | KLK5KLK7L3MBTL1CTSSCTSK | |
| SCHEMBL4416689 | 0.77 | KLK5 (0.64) | KLK5KLK7L3MBTL1CTSSCTSK | |
| SCHEMBL4416687 | 0.77 | KLK5 (0.64) | KLK5KLK7L3MBTL1CTSSCTSK | |
| SCHEMBL31291788 | 0.76 | HDAC4 (0.63) | KLK5KLK7L3MBTL1CTSSCTSK | |
| SCHEMBL9383811 | 0.75 | CTSS (0.58) | SCN9ACTSSCTSKCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563043-A | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-04-02 | — | — | CN | disclosed |