Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656762 | 0.80 | EPHX1 (0.50) | GNAI3GNAO1GNAI1EPHX1NPSR1 | |
| SCHEMBL28291327 | 0.76 | EPHX1 (0.50) | GNAI3GNAO1GNAI1EPHX1NPSR1 | |
| SCHEMBL15447812 | 0.76 | NPSR1 (0.68) | GNAI3GNAO1GNAI1EPHX1NPSR1 | |
| Hydrochloric Acid SCHEMBL2967152 | 0.76 | GNAI3 (0.47) | GNAI3GNAO1GNAI1EPHX1NPSR1 | |
| SCHEMBL1428636 | 0.75 | CHRM3 (0.46) | CHRM3 | |
| SCHEMBL28857546 | 0.75 | NPSR1 (0.34) | NPSR1POLBKMT2AMEN1ATM | |
| SCHEMBL4070701 | 0.74 | EPHX1 (0.55) | GNAI3GNAO1GNAI1EPHX1NPSR1 | |
| SCHEMBL27791277 | 0.74 | ITGB3 (0.41) | GNAI3GNAO1GNAI1EPHX1KMT2A | |
| SCHEMBL21882064 | 0.73 | EPHX1 (0.53) | GNAI3GNAO1GNAI1EPHX1NPSR1 | |
| SCHEMBL8230248 | 0.73 | EPHX1 (0.53) | GNAI3GNAO1GNAI1EPHX1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563043-A | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-04-02 | — | — | CN | disclosed |