Coumarin

Coumarin

SCHEMBL28291423

O=c1ccc2ccccc2o1.c1ccc2nccnc2c1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.71
CA9 Q16790 6/20 0.71
CA1 P00915 4/20 0.71
CA2 P00918 3/20 0.71
CA3 P07451 3/20 0.71
CA4 P22748 3/20 0.71
CA7 P43166 3/20 0.71
CA14 Q9ULX7 3/20 0.71
TDP1 Q9NUW8 3/20 0.71
MCL1 Q07820 3/20 0.71
CA5A P35218 2/20 0.71
CA5B Q9Y2D0 2/20 0.71
LMNA P02545 2/20 0.71
CA6 P23280 2/20 0.71
SOST Q9BQB4 1/20 0.71
NCOA1 Q15788 1/20 0.46
PGR P06401 2/20 0.45
CYP19A1 P11511 2/20 0.44
ALDH1A1 P00352 5/20 0.42
HPGD P15428 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coumarin SCHEMBL1377362 0.90 CA12 (0.67) CA12CA9CA1CA2CA3
Coumarin SCHEMBL30733982 0.90 CA12 (0.67) CA12CA9CA1CA2CA3
Coumarin SCHEMBL28314951 0.88 CA12 (0.65) CA12CA9CA1CA2CA3
Coumarin SCHEMBL3441294 0.84 CA12 (1.00) CA12CA9CA1CA2CA3
Coumarin SCHEMBL28886137 0.84 CA12 (1.00) CA12CA9CA1CA2CA3
Coumarin SCHEMBL6252 0.84 CA12 (1.00) CA12CA9CA1CA2CA3
Coumarin SCHEMBL621751 0.84 CA12 (1.00) CA12CA9CA1CA2CA3
Coumarin SCHEMBL29385611 0.84 CA12 (1.00) CA12CA9CA1CA2CA3
Coumarin SCHEMBL1038138 0.84 CA12 (1.00) CA12CA9CA1CA2CA3
Coumarin SCHEMBL2301559 0.82 CA12 (0.95) CA12CA9CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109593087-A A kind of multichannel distinguishes detection Cys/Hcy, GSH and H simultaneously2Design, synthesis and the application of the fluorescence probe of S 中南大学 2019-04-09 CN disclosed