SCHEMBL28291503

SCHEMBL28291503

NS(=O)(=O)N(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.48
TSHR P16473 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
POLB P06746 1/20 0.44
CYP3A4 P08684 1/20 0.44
PARP1 P09874 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C19 P33261 1/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CA2 P00918 4/20 0.43
CA12 O43570 3/20 0.43
CA1 P00915 3/20 0.43
CA9 Q16790 3/20 0.43
CA14 Q9ULX7 2/20 0.43
CA7 P43166 1/20 0.43
MAOA P21397 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11832256 0.82 HSD11B1 (0.52) HSD11B1TSHRTDP1L3MBTL1POLB
SCHEMBL974470 0.81 HSD11B1 (0.47) HSD11B1TSHRTDP1L3MBTL1POLB
SCHEMBL11288881 0.79 HSD11B1 (0.65) HSD11B1TSHRTDP1L3MBTL1POLB
SCHEMBL28263941 0.78 L3MBTL1 (0.45) HSD11B1TSHRTDP1L3MBTL1POLB
SCHEMBL11828717 0.77 HSD11B1 (0.67) HSD11B1TSHRL3MBTL1MAPTCYP2C19
SCHEMBL10915389 0.76 HSD11B1 (0.47) HSD11B1TSHRTDP1L3MBTL1POLB
SCHEMBL23699763 0.75 HSD11B1 (0.50) HSD11B1TSHRL3MBTL1POLBCES2
SCHEMBL11825751 0.74 HSD11B1 (0.62) HSD11B1TSHRL3MBTL1MAPTCYP2C19
SCHEMBL23733154 0.74 HSD11B1 (0.62) HSD11B1TSHRL3MBTL1MAPTCYP2C19
SCHEMBL1021022 0.74 HSD11B1 (0.45) HSD11B1TSHRTDP1L3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111517996-B Preparation method and preparation intermediate of benzoyl sulfamoyl benzamide 河北兰升生物科技有限公司 2023-08-15 CN disclosed
CN-111517996-B Preparation method and preparation intermediate of benzoyl sulfamoyl benzamide 河北兰升生物科技有限公司 2023-08-15 CN disclosed
CN-111517996-A Preparation method and preparation intermediate of benzoyl sulfamoyl benzamide 河北兰升生物科技有限公司 2020-08-11 CN disclosed
CN-111517996-A Preparation method and preparation intermediate of benzoyl sulfamoyl benzamide 河北兰升生物科技有限公司 2020-08-11 CN disclosed
CN-109640653-A Method for reducing crop damage 拜耳作物科学股份公司 2019-04-16 CN disclosed