Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489012 | 0.83 | HSD11B1 (0.47) | HSD11B1TSHRTDP1L3MBTL1POLB | |
| SCHEMBL28730355 | 0.82 | HSD11B1 (0.50) | HSD11B1TSHRTDP1L3MBTL1POLB | |
| SCHEMBL28291503 | 0.81 | HSD11B1 (0.48) | HSD11B1TSHRTDP1L3MBTL1POLB | |
| SCHEMBL11288881 | 0.78 | HSD11B1 (0.65) | HSD11B1TSHRTDP1L3MBTL1POLB | |
| SCHEMBL8042370 | 0.77 | CES1 (0.42) | HSD11B1TSHRTDP1L3MBTL1POLB | |
| SCHEMBL9026301 | 0.77 | HSD11B1 (0.46) | HSD11B1TSHRTDP1L3MBTL1POLB | |
| SCHEMBL3720381 | 0.75 | TDP1 (0.52) | HSD11B1TSHRTDP1L3MBTL1POLB | |
| SCHEMBL64274 | 0.75 | TDP1 (0.52) | HSD11B1TSHRTDP1L3MBTL1POLB | |
| SCHEMBL10915389 | 0.75 | HSD11B1 (0.47) | HSD11B1TSHRTDP1L3MBTL1POLB | |
| SCHEMBL8135824 | 0.74 | GAA (0.46) | HSD11B1TSHRTDP1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232421-B2 | Bifunctional phenyl ISO (THIO) cyanates, processes and intermediates for their preparation | BASF AKTIENGESELLSCHAFT (DE) | 2012-07-31 | — | — | US | claimed |
| US-7820846-B2 | by phosgenation of an aminobenzoylsulfamic acid amide intermediate; prepared from a p-nitrobenzoyl chloride or benzoate and a sulfamic acid amide and reducing the nitrobenzoylsulfamic acid amide; isocyanates are crop protection agents | BASF AKTIENGESELLSCHAFT (DE) | 2010-10-26 | — | — | US | claimed |
| CN-100368392-C | Bifunctional phenyliso(thio)cyanates, processes and intermediates products for their preparation | BASF AG (DE) | 2008-02-13 | — | — | CN | claimed |
| US-20060004220-A1 | Bifunctional phenyliso(thio)cyanates, processes and intermediates products for their Preparation | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-05 | — | — | US | claimed |
| US-20260085051-A1 | PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID | ADAMA AGAN LTD. (IL) | 2026-03-26 | — | — | US | disclosed |
| EP-4313954-B1 | PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID | ADAMA AGAN LTD (IL) | 2025-10-15 | — | — | EP | disclosed |
| US-20240217915-A1 | PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID | ADAMA AGAN LTD. (IL) | 2024-07-04 | — | — | US | disclosed |
| EP-4313954-A1 | PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID | Adama Agan Ltd. (IL) | 2024-02-07 | — | — | EP | disclosed |
| US-11219625-B2 | Inhibitors of N-linked glycosylation and methods using same | YALE UNIVERSITY (US) | 2022-01-11 | — | — | US | disclosed |
| US-20190000858-A1 | Inhibitors of N-Linked Glycosylation and Methods Using Same | YALE UNIVERSITY | 2019-01-03 | — | — | US | disclosed |
| WO-2017019540-A2 | INHIBITORS OF N-LINKED GLYCOSYLATION AND METHODS USING SAME | YALE UNIVERSITY (US) | 2017-02-02 | — | — | WO | disclosed |
| US-8541611-B2 | Bifunctional phenyl iso(thio)cyanates, processes and intermediates products for their preparation | BASF AKTIENGESELLSCHAFT (DE) | 2013-09-24 | — | — | US | disclosed |
| US-8232421-B2 | Bifunctional phenyl ISO (THIO) cyanates, processes and intermediates for their preparation | BASF AKTIENGESELLSCHAFT (DE) | 2012-07-31 | — | — | US | disclosed |
| US-20110009640-A1 | BIFUNCTIONAL PHENYL ISO (THIO) CYANATES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION | BASF AKTIENGESELLSCHAFT (DE) | 2011-01-13 | — | — | US | disclosed |
| US-7820846-B2 | by phosgenation of an aminobenzoylsulfamic acid amide intermediate; prepared from a p-nitrobenzoyl chloride or benzoate and a sulfamic acid amide and reducing the nitrobenzoylsulfamic acid amide; isocyanates are crop protection agents | BASF AKTIENGESELLSCHAFT (DE) | 2010-10-26 | — | — | US | disclosed |
| CN-100368392-C | Bifunctional phenyliso(thio)cyanates, processes and intermediates products for their preparation | BASF AG (DE) | 2008-02-13 | — | — | CN | disclosed |
| US-20060004220-A1 | Bifunctional phenyliso(thio)cyanates, processes and intermediates products for their Preparation | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-05 | — | — | US | disclosed |
| CN-1717388-A | Bifunctional phenyliso(thio)cyanates, processes and intermediates products for their preparation | BASF AG (DE) | 2006-01-04 | — | — | CN | disclosed |
| EP-1560810-A1 | BIFUNCTIONAL PHENYLISO(THIO)CYANATES; METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004039768-A1 | BIFUNCTIONAL PHENYLISO(THIO)CYANATES; METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190000858-A1 | Inhibitors of N-Linked Glycosylation and Methods Using Same | ENGASE, FUT5, B3GNT2 | HSD11B1 2028/4885TSHR 4229/4885TDP1 1593/4885 |
| US-20110009640-A1 | BIFUNCTIONAL PHENYL ISO (THIO) CYANATES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION | TST, IDO1, IDO2 | HSD11B1 2177/4885TSHR 3144/4885TDP1 550/4885 |
| US-11219625-B2 | Inhibitors of N-linked glycosylation and methods using same | ENGASE, FUT5, B3GNT2 | HSD11B1 2028/4885TSHR 4229/4885TDP1 1593/4885 |
| US-20240217915-A1 | PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID | CYP4F12, COXFA4, NDUFS5 | HSD11B1 4394/4885TSHR 2171/4885TDP1 2459/4885 |
| US-20260085051-A1 | PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID | FOSB, DDT, NPM1 | HSD11B1 3306/4885TSHR 2588/4885TDP1 534/4885 |
| US-20060004220-A1 | Bifunctional phenyliso(thio)cyanates, processes and intermediates products for their Preparation | TST, TMT1A, IDO1 | HSD11B1 2088/4885TSHR 2570/4885TDP1 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.