Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28118256 | 0.74 | AR (0.64) | ARAOC3MEN1KMT2A | |
| SCHEMBL28291525 | 0.73 | AR (0.42) | ARMEN1KMT2A | |
| SCHEMBL28118706 | 0.72 | AR (0.65) | ARMEN1KMT2A | |
| SCHEMBL28872808 | 0.72 | AOC3 (0.47) | ARAOC3 | |
| SCHEMBL28118767 | 0.72 | AR (0.39) | ARAOC3MEN1KMT2A | |
| SCHEMBL27350499 | 0.70 | DDB1 (0.42) | MEN1KMT2ADDB1CRBN | |
| SCHEMBL29872795 | 0.68 | MEN1 (0.61) | ARMEN1KMT2A | |
| SCHEMBL27468096 | 0.67 | KDM1A (0.39) | — | |
| SCHEMBL28088762 | 0.66 | ALDH1A1 (0.47) | — | |
| SCHEMBL8728249 | 0.65 | MAPT (0.46) | MEN1KMT2ADDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573921-B | Imidazolidine-2, 4-dione derivatives | 博福-益普生（天津）制药有限公司 | 2019-05-07 | — | — | CN | disclosed |