Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987454 | 0.78 | AR (0.45) | ARSIRT6HTR2CHTR2BMEN1 | |
| SCHEMBL6990671 | 0.77 | AR (0.41) | ARSIRT6HTR2CHTR2BMEN1 | |
| SCHEMBL28872808 | 0.77 | AOC3 (0.47) | ARAOC3SIRT6HTR2CTRPV1 | |
| SCHEMBL28118768 | 0.76 | AR (0.41) | ARSIRT6HTR2CHTR2BMEN1 | |
| SCHEMBL11093931 | 0.75 | SIRT6 (0.60) | ARSIRT6MEN1LMNATP53 | |
| SCHEMBL28118706 | 0.72 | AR (0.65) | ARMEN1LMNATP53CYP1A2 | |
| SCHEMBL28118256 | 0.72 | AR (0.64) | ARAOC3MEN1LMNATP53 | |
| SCHEMBL28291524 | 0.72 | AR (0.39) | ARAOC3MEN1KMT2A | |
| SCHEMBL15264125 | 0.65 | MGLL (0.47) | AOC3FAAH | |
| SCHEMBL27468096 | 0.64 | KDM1A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573921-B | Imidazolidine-2, 4-dione derivatives | 博福-益普生（天津）制药有限公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-106573921-A | Novel imidazolidine-2, 4-dione derivatives | 博福-益普生（天津）制药有限公司 | 2017-04-19 | — | — | CN | disclosed |