Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28118767 | 0.77 | AR (0.39) | AOC3HTR2CARSIRT6FAAH | |
| SCHEMBL28118256 | 0.74 | AR (0.64) | AOC3AR | |
| SCHEMBL28872810 | 0.73 | HTR6 (0.42) | AOC3HTR3EHTR3BALDH1A1HTR1D | |
| SCHEMBL28291524 | 0.72 | AR (0.39) | AOC3AR | |
| SCHEMBL11177028 | 0.70 | HTR3E (0.58) | AOC3HTR3EHTR3BALDH1A1HTR1D | |
| SCHEMBL28118706 | 0.68 | AR (0.65) | AR | |
| SCHEMBL2928855 | 0.67 | HTR3E (0.55) | AOC3HTR3EHTR3BALDH1A1HTR1D | |
| SCHEMBL27468096 | 0.67 | KDM1A (0.39) | — | |
| SCHEMBL1432376 | 0.66 | HTR3E (0.54) | AOC3HTR3EHTR3BALDH1A1HTR1D | |
| SCHEMBL11627069 | 0.66 | ADRB1 (0.65) | AOC3HTR3EHTR3BALDH1A1HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573921-B | Imidazolidine-2, 4-dione derivatives | 博福-益普生（天津）制药有限公司 | 2019-05-07 | — | — | CN | disclosed |