Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16879321 | 0.74 | AR (0.65) | ARPKMRAB9AMEN1KMT2A | |
| SCHEMBL1191623 | 0.73 | AR (0.68) | ARRAB9AMEN1KMT2A | |
| SCHEMBL28291524 | 0.73 | AR (0.39) | ARMEN1KMT2A | |
| SCHEMBL28118768 | 0.72 | AR (0.41) | ARPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL28872810 | 0.71 | HTR6 (0.42) | PKMRAB9A | |
| SCHEMBL27350499 | 0.70 | DDB1 (0.42) | PTGS2MEN1KMT2A | |
| SCHEMBL19410379 | 0.69 | LMNA (0.51) | PTGS2 | |
| SCHEMBL29872795 | 0.69 | MEN1 (0.61) | ARRAB9AMEN1KMT2A | |
| SCHEMBL25316229 | 0.69 | PIK3CD (0.43) | ARPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL4639494 | 0.69 | L3MBTL1 (0.56) | ARPIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573921-B | Imidazolidine-2, 4-dione derivatives | 博福-益普生（天津）制药有限公司 | 2019-05-07 | — | — | CN | disclosed |