Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.43 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205059 | 0.88 | TAAR1 (0.50) | TAAR1IDO1LTA4HMBOAT4VKORC1 | |
| SCHEMBL22288569 | 0.83 | TAAR1 (0.46) | TAAR1IDO1LTA4HMBOAT4VKORC1 | |
| SCHEMBL28291656 | 0.81 | TAAR1 (0.56) | TAAR1IDO1LTA4HMAOB | |
| SCHEMBL10702190 | 0.77 | CYP3A4 (0.59) | MAOB | |
| SCHEMBL2096666 | 0.76 | SRD5A2 (0.59) | TAAR1IDO1LTA4HMAOBSRD5A2 | |
| SCHEMBL3048506 | 0.75 | KIF11 (0.64) | TAAR1IDO1LTA4HMAOBSRD5A2 | |
| SCHEMBL6557214 | 0.74 | CALM1 (0.52) | NSD2IDO1MAOB | |
| SCHEMBL8378077 | 0.74 | MBOAT4 (0.50) | NSD2TAAR1IDO1LTA4HMBOAT4 | |
| SCHEMBL11781865 | 0.74 | HTR2A (0.39) | TAAR1IDO1LTA4HMAOB | |
| SCHEMBL28273575 | 0.74 | CYP19A1 (0.49) | TAAR1IDO1LTA4HSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641836-A | Fluorinated 2- amino -4- (substituted amino) carbanilate derivative | 赛弗卢尔生命科学公司 | 2019-04-16 | — | — | CN | disclosed |