Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 4/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22288569 | 0.90 | TAAR1 (0.46) | TAAR1IDO1LTA4HKIF11MAOB | |
| SCHEMBL28291649 | 0.88 | NSD2 (0.48) | TAAR1IDO1LTA4HKIF11MAOB | |
| SCHEMBL2096666 | 0.79 | SRD5A2 (0.59) | TAAR1IDO1LTA4HKIF11MAOB | |
| SCHEMBL3048506 | 0.78 | KIF11 (0.64) | TAAR1IDO1LTA4HKIF11MAOB | |
| SCHEMBL8378077 | 0.77 | MBOAT4 (0.50) | TAAR1IDO1LTA4HMAOBMBOAT4 | |
| SCHEMBL27912332 | 0.76 | SKP2 (0.46) | TAAR1IDO1LTA4HMAOBMBOAT4 | |
| SCHEMBL4528900 | 0.75 | CYP3A4 (0.65) | MAOBKMT2A | |
| SCHEMBL7203852 | 0.72 | MBOAT4 (0.37) | TAAR1IDO1LTA4HMBOAT4 | |
| SCHEMBL5255445 | 0.71 | ALDH1A1 (0.59) | TAAR1IDO1LTA4HKIF11MAOB | |
| SCHEMBL7935401 | 0.71 | SRD5A2 (0.52) | TAAR1IDO1LTA4HKIF11MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003076388-A2 | BIS-ANILINE DERIVATIVES USEFUL AS POTASSIUM CHANNELS MODULATORS | 4SC AG (DE) | 2003-09-18 | — | — | WO | disclosed |