Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | UBE2N | P61088 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1062877 | 0.84 | ELOVL1 (0.50) | L3MBTL1KDM4ENPC1RAB9ALMNA | |
| SCHEMBL19778587 | 0.82 | KMT2A (0.54) | KMT2AL3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL15754826 | 0.81 | NPC1 (0.60) | KMT2AL3MBTL1KDM4ECHRNA7NPC1 | |
| SCHEMBL14150735 | 0.80 | KMT2A (0.64) | KMT2AL3MBTL1KDM4EUBE2NMEN1 | |
| SCHEMBL168402 | 0.79 | KMT2A (0.54) | KMT2AL3MBTL1KDM4EUBE2NHDAC3 | |
| SCHEMBL13832646 | 0.77 | KDM4E (0.50) | KMT2AL3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL168303 | 0.77 | L3MBTL1 (0.49) | KMT2AL3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL24380270 | 0.77 | CA1 (0.52) | KMT2ACHRNA7NPC1RAB9ALMNA | |
| SCHEMBL30882479 | 0.72 | HPGDS (0.49) | KMT2AKDM4ECHRNA7NPC1RAB9A | |
| SCHEMBL5962907 | 0.72 | SCN4A (0.49) | KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641890-A | Isocitric dehydrogenase (IDH) inhibitor | 上海迈同生物科技有限公司 | 2019-04-16 | — | — | CN | disclosed |