Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28291870 | 0.87 | LMNA (0.52) | SMN1; SMN2ALDH1A1L3MBTL1LMNACYP1A2 | |
| SCHEMBL5929588 | 0.83 | L3MBTL1 (0.47) | SMN1; SMN2ALDH1A1L3MBTL1LMNACYP1A2 | |
| SCHEMBL28291731 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1L3MBTL1CYP1A2RAB9A | |
| SCHEMBL8341741 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1L3MBTL1LMNACYP1A2 | |
| SCHEMBL28535906 | 0.74 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1L3MBTL1RAB9ANPC1 | |
| SCHEMBL22420949 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1LMNAAHR | |
| SCHEMBL21742085 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1LMNACYP1A2RAB9A | |
| SCHEMBL21742006 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1L3MBTL1LMNACYP1A2 | |
| SCHEMBL852344 | 0.71 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1L3MBTL1LMNARAB9A | |
| SCHEMBL21742045 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1L3MBTL1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608390-B | Synthesis method of chiral quaternary carbon pyridine beta-hydroxy ester compound | 温州大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-109608390-A | A kind of synthetic method of chirality quaternary carbon pyridines β hydroxyl esters compound | 温州大学 | 2019-04-12 | — | — | CN | disclosed |