Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.45 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25685990 | 0.83 | SPHK2 (0.57) | SPHK2SPHK1HRH3 | |
| SCHEMBL28290323 | 0.81 | SPHK2 (0.50) | SPHK2SPHK1HRH3TRPV6SIGMAR1 | |
| SCHEMBL28290374 | 0.81 | OPRK1 (0.56) | SPHK2SPHK1HRH3TRPV6SIGMAR1 | |
| SCHEMBL7246899 | 0.80 | MITF (0.54) | SIGMAR1 | |
| SCHEMBL28872406 | 0.78 | SLC18A2 (0.53) | SPHK2SPHK1HRH3 | |
| SCHEMBL28291778 | 0.77 | HRH3 (0.59) | MAOBSPHK2SPHK1HRH3TRPV6 | |
| SCHEMBL8267634 | 0.76 | FFAR1 (0.49) | MAOBSPHK2SPHK1OPRK1 | |
| SCHEMBL28290308 | 0.75 | HRH3 (0.70) | SPHK2SPHK1HRH3SIGMAR1 | |
| SCHEMBL23996803 | 0.73 | SPHK1 (0.65) | SPHK2SPHK1 | |
| SCHEMBL7248042 | 0.73 | MITF (0.47) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641878-A | DIPROVOCIM: a new class of effective TLR agonist | 斯克里普斯研究学院 | 2019-04-16 | — | — | CN | disclosed |