Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | DHFR | P00374 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 6/20 | 0.56 |
| ▸ | CA2 | P00918 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2928482 | 0.86 | SMN1; SMN2 (0.66) | TSHRSMN1; SMN2DHFRTDP1CA1 | |
| SCHEMBL11557623 | 0.85 | CA1 (0.58) | TSHRSMN1; SMN2DHFRTDP1CA1 | |
| SCHEMBL13966984 | 0.85 | SMN1; SMN2 (0.59) | TSHRSMN1; SMN2DHFRTDP1CA1 | |
| SCHEMBL791784 | 0.83 | L3MBTL1 (0.62) | TSHRSMN1; SMN2DHFRTDP1CA1 | |
| SCHEMBL10285030 | 0.82 | ALDH1A1 (0.68) | TSHRSMN1; SMN2DHFRTDP1CA1 | |
| SCHEMBL12700752 | 0.81 | SMN1; SMN2 (0.62) | TSHRSMN1; SMN2DHFRTDP1CA2 | |
| Sulfacetamide SCHEMBL28122264 | 0.80 | SMN1; SMN2 (1.00) | TSHRSMN1; SMN2DHFRTDP1CA1 | |
| Sulfacetamide SCHEMBL40863 | 0.80 | SMN1; SMN2 (1.00) | TSHRSMN1; SMN2DHFRTDP1CA1 | |
| SCHEMBL11565568 | 0.79 | ALDH1A1 (0.66) | TSHRSMN1; SMN2TDP1CA1CA2 | |
| Sulfacetamide SCHEMBL5015229 | 0.79 | SMN1; SMN2 (0.69) | TSHRSMN1; SMN2DHFRTDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761944-A | A kind of chrysin amide derivatives and preparation method thereof and medical usage | 武汉翼博济生生物科技有限公司 | 2019-05-17 | — | — | CN | disclosed |