Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3388501 | 0.89 | LMNA (0.45) | MEN1KMT2ACYP2A6MAOAMAOB | |
| SCHEMBL12945193 | 0.78 | KMT2A (0.50) | MEN1KMT2ACYP2A6MAOAMAOB | |
| SCHEMBL20622381 | 0.78 | KMT2A (0.50) | MEN1KMT2ACYP2A6MAOAMAOB | |
| SCHEMBL29960722 | 0.78 | MEN1 (0.50) | MEN1KMT2ACYP2A6MAOAMAOB | |
| SCHEMBL14408830 | 0.78 | MEN1 (0.50) | MEN1KMT2ACYP2A6MAOAMAOB | |
| SCHEMBL20622393 | 0.75 | L3MBTL1 (0.58) | MEN1KMT2ACES1ALDH1A1L3MBTL1 | |
| SCHEMBL642025 | 0.74 | NOTUM (0.70) | MEN1KMT2ANOTUMHTTLMNA | |
| SCHEMBL20619640 | 0.74 | MEN1 (0.46) | MEN1KMT2ACYP2A6MAOAMAOB | |
| SCHEMBL25429945 | 0.74 | ALDH1A1 (0.50) | MEN1KMT2ANOTUMHTTLMNA | |
| SCHEMBL8823921 | 0.72 | SMN1; SMN2 (0.53) | MEN1KMT2ANOTUMHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294562-B | A kind of preparation method of the chloro- 5- oxo -2,3,4,5- tetrahydro -1H-1- benzazepine of 7- | 长春吉大天元化学技术股份有限公司 | 2019-04-16 | — | — | CN | claimed |
| CN-105294562-B | A kind of preparation method of the chloro- 5- oxo -2,3,4,5- tetrahydro -1H-1- benzazepine of 7- | 长春吉大天元化学技术股份有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-105294562-B | A kind of preparation method of the chloro- 5- oxo -2,3,4,5- tetrahydro -1H-1- benzazepine of 7- | 长春吉大天元化学技术股份有限公司 | 2019-04-16 | — | — | CN | disclosed |