SCHEMBL28292426

SCHEMBL28292426

C=C(C)C(=O)Oc1ccc(C(C)(C)c2ccc(OC(=O)C(=C)C)cc2C(C)C)c(C(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.42
KMT2A Q03164 2/20 0.40
ATM Q13315 1/20 0.40
PLA2G1B P04054 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
ALDH1A1 P00352 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL65219 0.82 ELANE (0.41) ELANEKMT2AATMALDH1A1KDM4E
SCHEMBL29771152 0.82 ELANE (0.41) ELANEKMT2AATMALDH1A1KDM4E
SCHEMBL15495977 0.81 THRB (0.47) ELANE
SCHEMBL4639822 0.78 KDM4E (0.43) ELANEKMT2AATMTDP1KDM4E
SCHEMBL346348 0.77 ELANE (0.37) ELANEKMT2AATMTDP1KDM4E
SCHEMBL27657742 0.75 ELANE (0.40) ELANEKMT2AATMPLA2G1BTDP1
SCHEMBL10987623 0.75 ELANE (0.38) ELANEKMT2AATMTDP1KDM4E
SCHEMBL23581567 0.75 ELANE (0.36) ELANEKMT2AATMTDP1ALDH1A1
SCHEMBL10437293 0.73 ELANE (0.39) ELANEKMT2AATMTDP1ALDH1A1
SCHEMBL10880960 0.73 ELANE (0.34) ELANEKMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110418628-A Curable composition for dental applications and its manufacturing method TOKUYAMA DENTAL CORP 2019-11-05 CN disclosed
CN-110392563-A Photocurable composition and dental prosthetic material 株式会社德山齿科 2019-10-29 CN disclosed
CN-108289795-B Curable composition and dental filling/repairing material 株式会社德山齿科 2019-05-17 CN disclosed