Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29771152 | 1.00 | ELANE (0.41) | ELANEKMT2AATMALDH1A1POLB | |
| SCHEMBL20636771 | 0.88 | ALDH1A1 (0.33) | ELANEKMT2AALDH1A1POLBIRAK4 | |
| SCHEMBL10880960 | 0.84 | ELANE (0.34) | ELANEKMT2AATMPOLB | |
| SCHEMBL346348 | 0.83 | ELANE (0.37) | ELANEKMT2AATMPOLBKDM4E | |
| SCHEMBL4639822 | 0.82 | KDM4E (0.43) | ELANEKMT2AATMPOLBKDM4E | |
| SCHEMBL32674606 | 0.82 | THRB (0.40) | ELANEKMT2AALDH1A1POLBIRAK4 | |
| SCHEMBL11133256 | 0.82 | THRB (0.40) | ELANEKMT2AALDH1A1POLBIRAK4 | |
| SCHEMBL28292426 | 0.82 | ELANE (0.42) | ELANEKMT2AATMALDH1A1KDM4E | |
| SCHEMBL23581567 | 0.81 | ELANE (0.36) | ELANEKMT2AATMALDH1A1POLB | |
| SCHEMBL11108090 | 0.80 | ELANE (0.33) | ELANEKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 499 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | VOCO GMBH (DE) | 2024-05-28 | — | — | US | claimed |
| US-20240108555-A1 | UNREACTIVE TRANSFER SPLINTS | VOCO GMBH (DE) | 2024-04-04 | — | — | US | claimed |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | VOCO GMBH (DE) | 2021-02-25 | — | — | US | claimed |
| EP-2623087-B1 | Dental composite materials containing tricyclic plasticisers | VOCO GMBH (DE) | 2019-07-17 | — | — | EP | claimed |
| EP-2623086-B1 | Curable mixture comprising plasticisers with a polyalicyclic structure element for use in the production of dental materials. | VOCO GMBH (DE) | 2019-07-10 | — | — | EP | claimed |
| US-9925124-B2 | Dental composition suitable for grinding with automatic grinding apparatus | KABUSHIKI KAISHA SHOFU (JP) | 2018-03-27 | — | — | US | claimed |
| US-9314408-B2 | Dental composite materials comprising tricyclic plasticizers | VOCO GMBH (DE) | 2016-04-19 | — | — | US | claimed |
| US-20130203884-A1 | DENTAL COMPOSITE MATERIALS COMPRISING TRICYCLIC PLASTICIZERS | VOCO GMBH (DE) | 2013-08-08 | — | — | US | claimed |
| EP-2623087-A2 | Dental composite materials containing tricyclic plasticisers | VOCO GmbH (DE) | 2013-08-07 | — | — | EP | claimed |
| EP-2623086-A2 | Curable mixture comprising plasticisers with a polyalicyclic structure element for use in the production of dental materials. | VOCO GmbH (DE) | 2013-08-07 | — | — | EP | claimed |
| EP-4091578-B1 | METHOD FOR PRODUCING PLATE DENTURE | TOKUYAMA DENTAL CORP (JP) | 2024-10-09 | — | — | EP | disclosed |
| WO-2024150826-A1 | DENTAL COMPOSITION | クラレノリタケデンタル株式会社 | 2024-07-18 | — | — | WO | disclosed |
| US-12030970-B2 | Curable composition and stereolithographic resin composition comprising same | KURARAY CO., LTD. (JP) | 2024-07-09 | — | — | US | disclosed |
| US-20240199494-A1 | ZIRCONIA MOLDED BODY, ZIRCONIA PRE-SINTERED BODY, AND ZIRCONIA SINTERED BODY, AND METHODS OF PRODUCTION THEREOF | Kuraray Noritake Dental lnc. (JP) | 2024-06-20 | — | — | US | disclosed |
| US-20240180788-A1 | PHOTOCATIONICALLY CURABLE COMPOSITION | TOKUYAMA DENTAL CORPORATION (JP) | 2024-06-06 | — | — | US | disclosed |
| US-5260476-A | Dental restoration | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5171763-A | A dental composite of a monomer containing poly(3,4-carboxylic benzoic acid and acrylic ester moities, an ion leachable filler and an initiator; high adhesion and strength; discoloration inhibition | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1992-12-15 | — | — | US | disclosed |
| US-4394494-A | DIURETHANE TETRAACRYLATES AS POLYMERIZABLE MONOMERS | LION CORPORATION (JP) | 1983-07-19 | — | — | US | disclosed |
| US-4388421-A | PRIMERS | LION CORPORATION (JP) | 1983-06-14 | — | — | US | disclosed |
| US-4383052-A | 1-Methacryloxyethane-1,1-diphosphonic acid and its salts and dental adhesive composition containing same | LION CORPORATION (JP) | 1983-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | NCAPH, RCC1, NCAPD2 | ELANE 1186/4885KMT2A 628/4885ATM 3096/4885 |
| US-20240180788-A1 | PHOTOCATIONICALLY CURABLE COMPOSITION | CRY1, CRY2, TYR | ELANE 4582/4885KMT2A 491/4885ATM 2926/4885 |
| US-12030970-B2 | Curable composition and stereolithographic resin composition comprising same | ARL1, ASH2L, VCL | ELANE 2345/4885KMT2A 1501/4885ATM 3316/4885 |
| US-20240108555-A1 | UNREACTIVE TRANSFER SPLINTS | MATR3, SUGT1, DIMT1 | ELANE 4304/4885KMT2A 124/4885ATM 2217/4885 |
| US-20130203884-A1 | DENTAL COMPOSITE MATERIALS COMPRISING TRICYCLIC PLASTICIZERS | CAD, PBRM1, PCBP1 | ELANE 4105/4885KMT2A 2690/4885ATM 2055/4885 |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | NCAPH, RCC1, NCAPD2 | ELANE 1186/4885KMT2A 628/4885ATM 3096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.