Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.31 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28940874 | 0.80 | MEN1 (0.35) | KIF11KMT2AMEN1MAPK8SIRT6 | |
| SCHEMBL26093046 | 0.79 | KMT2A (0.41) | KIF11KMT2AMEN1MAPTPARP10 | |
| SCHEMBL28375297 | 0.79 | KMT2A (0.41) | KIF11KMT2AMEN1MAPTPARP10 | |
| SCHEMBL28941178 | 0.78 | KIF11 (0.34) | KIF11KMT2AMEN1CYP4F2CYP4A11 | |
| SCHEMBL9519545 | 0.78 | AOC3 (0.39) | KIF11KMT2AMEN1MAPTPARP10 | |
| SCHEMBL28292551 | 0.78 | LNPEP (0.46) | KMT2AMEN1LNPEP | |
| SCHEMBL28292591 | 0.76 | KIF11 (0.39) | KIF11KMT2AMEN1MAPTPARP10 | |
| SCHEMBL28292626 | 0.76 | KMT2A (0.39) | KIF11KMT2AMEN1PPARAMAPT | |
| SCHEMBL26640548 | 0.76 | SYK (0.39) | KIF11KMT2AMEN1MAPTPARP10 | |
| SCHEMBL28286228 | 0.75 | KMT2A (0.49) | KIF11KMT2AMEN1PARP10SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-109689647-A | The compound that bicyclic heteroaryl replaces | 百时美施贵宝公司 | 2019-04-26 | — | — | CN | disclosed |