Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26093046 | 0.86 | KMT2A (0.41) | KMT2AMEN1FFAR1KIF11OPRM1 | |
| SCHEMBL28375297 | 0.83 | KMT2A (0.41) | KMT2AMEN1FFAR1KIF11OPRM1 | |
| SCHEMBL28365996 | 0.80 | PTGS2 (0.35) | KMT2AMEN1FFAR1KIF11ACACB | |
| SCHEMBL9519545 | 0.79 | AOC3 (0.39) | KMT2AMEN1FFAR1KIF11AOC3 | |
| SCHEMBL28723869 | 0.77 | MEN1 (0.38) | KMT2AMEN1KIF11 | |
| SCHEMBL26640548 | 0.76 | SYK (0.39) | KMT2AMEN1FFAR1KIF11ACACB | |
| SCHEMBL28292573 | 0.76 | KIF11 (0.36) | KMT2AMEN1FFAR1KIF11MAPT | |
| SCHEMBL28723920 | 0.75 | GCK (0.40) | KMT2AMEN1KIF11AOC3OPRM1 | |
| SCHEMBL28292605 | 0.75 | MEN1 (0.46) | KMT2AMEN1KIF11MAPTPARP10 | |
| SCHEMBL25253178 | 0.75 | PTGS2 (0.40) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-109689647-A | The compound that bicyclic heteroaryl replaces | 百时美施贵宝公司 | 2019-04-26 | — | — | CN | disclosed |