Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28637400 | 0.80 | ALDH1A1 (0.57) | MCL1ALDH1A1PRKDCKMT2AMAPT | |
| SCHEMBL28645900 | 0.79 | ALDH1A1 (0.48) | ALDH1A1PRKDCKMT2AMAPTMEN1 | |
| SCHEMBL24589799 | 0.79 | MAOB (0.55) | MCL1ALDH1A1PRKDCMAPTHSD17B3 | |
| SCHEMBL28656942 | 0.77 | HSD17B10 (0.46) | ALDH1A1PRKDCKMT2AMAPTMEN1 | |
| SCHEMBL22501691 | 0.77 | KDM4E (0.54) | MCL1ALDH1A1MAPTHSD17B3CYP3A4 | |
| SCHEMBL1937493 | 0.76 | HSD17B10 (0.51) | ALDH1A1PRKDCKMT2AMAPTMEN1 | |
| SCHEMBL1937101 | 0.75 | HSD17B10 (0.53) | ALDH1A1PRKDCKMT2AMAPTMEN1 | |
| SCHEMBL32677438 | 0.75 | HSD17B10 (0.53) | ALDH1A1PRKDCKMT2AMAPTMEN1 | |
| SCHEMBL18493216 | 0.74 | ALDH1A1 (0.54) | MCL1ALDH1A1MAPTHSD17B3CYP3A4 | |
| SCHEMBL28651740 | 0.74 | HSD17B10 (0.43) | ALDH1A1PRKDCKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109593084-B | Prolyl hydroxylase small-molecule photosensitive prodrug and preparation method and application thereof | 中国药科大学 | 2021-09-28 | — | — | CN | disclosed |
| CN-109593084-A | Photosensitive prodrug of prolyl hydroxylase small molecule and the preparation method and application thereof | 中国药科大学 | 2019-04-09 | — | — | CN | disclosed |