Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | L3MBTL3 | Q96JM7 | 8/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.44 |
| ▸ | L3MBTL4 | Q8NA19 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10293612 | 0.84 | EPHX1 (0.71) | EPHX1L3MBTL3ACHEKMT2AMEN1 | |
| SCHEMBL22542170 | 0.83 | KMT2A (0.65) | EPHX1L3MBTL3KMT2AMEN1ALDH1A1 | |
| SCHEMBL16003001 | 0.83 | MGLL (0.55) | EPHX1L3MBTL3ACHEKMT2AMEN1 | |
| SCHEMBL13866413 | 0.83 | EPHX1 (0.55) | EPHX1L3MBTL3ACHEKMT2APIK3R1 | |
| SCHEMBL4352489 | 0.82 | ACHE (0.70) | L3MBTL3ACHEKMT2AMEN1ALDH1A1 | |
| SCHEMBL16003020 | 0.81 | L3MBTL3 (0.51) | EPHX1L3MBTL3ACHEKMT2AMEN1 | |
| SCHEMBL16003042 | 0.81 | EPHX2 (0.62) | EPHX1KMT2AMEN1ALDH1A1EPHX2 | |
| SCHEMBL747025 | 0.80 | GRM5 (0.56) | EPHX1L3MBTL3ACHEALDH1A1MBTD1 | |
| SCHEMBL1921224 | 0.79 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL20883799 | 0.79 | ALDH1A1 (0.63) | EPHX1L3MBTL3KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104350055-B | Bicyclic heteroaryl derivatives and application thereof as MNK1 and MNK2 regulator | 新加坡科技研究局 | 2019-05-31 | — | — | CN | disclosed |