SCHEMBL282929

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10127041	0.89	CA1 (0.38)	POLBCA1CA2CA7JAK2
	SCHEMBL13071322	0.87	CA1 (0.37)	POLBCA1CA2CA7MEN1
	SCHEMBL10127221	0.87	CA1 (0.37)	POLBCA1CA2CA7MEN1
	SCHEMBL17069444	0.84	LMNA (0.47)	PPARGMAPTSYKZAP70
	SCHEMBL10127219	0.81	MAPKAPK2 (0.45)	CA1CA2CA7MEN1KMT2A
	SCHEMBL283679	0.79	CA1 (0.45)	POLBCA1CA2CA7MEN1
	SCHEMBL10127090	0.78	CA1 (0.48)	CA1CA2CA7JAK2MEN1
	SCHEMBL283538	0.78	RAB9A (0.46)	POLBMEN1KMT2APPARGMAPT
	SCHEMBL10127228	0.78	KIT (0.39)	POLBCA1CA2CA7PPARG
	SCHEMBL10126692	0.78	PPARG (0.47)	POLBCA1CA2CA7MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.