Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.32 |
| ▸ | GABRE | P78334 | 2/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.32 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4281970 | 0.79 | ALOX15 (0.46) | ALOX15LMNAALDH1A1HSD17B10MGAM | |
| SCHEMBL28292971 | 0.77 | — | — | |
| SCHEMBL9936911 | 0.77 | TSHR (0.40) | TSHRALOX15LMNAALDH1A1HSD17B10 | |
| SCHEMBL28294538 | 0.77 | TSHR (0.41) | TSHRALOX15LMNAALDH1A1GABRP | |
| SCHEMBL5544727 | 0.74 | TSHR (0.37) | TSHRALOX15LMNAALDH1A1HSD17B10 | |
| SCHEMBL28292935 | 0.74 | HCAR2 (0.36) | TSHRALOX15LMNAALDH1A1HSD17B10 | |
| SCHEMBL303947 | 0.74 | — | — | |
| SCHEMBL13155620 | 0.73 | TSHR (0.40) | TSHRALOX15LMNAALDH1A1HCAR2 | |
| SCHEMBL5330308 | 0.73 | TSHR (0.40) | TSHRALOX15LMNAALDH1A1HCAR2 | |
| SCHEMBL19123628 | 0.73 | TSHR (0.40) | TSHRHCAR2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651286-A | A kind of highly selective 4-(4- aminophenyl) morpholine -3- ketone synthetic method | 新发药业有限公司 | 2019-04-19 | — | — | CN | disclosed |