⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4281970 | 0.83 | ALOX15 (0.46) | — | |
| SCHEMBL28292928 | 0.77 | TSHR (0.37) | — | |
| SCHEMBL28292935 | 0.77 | HCAR2 (0.36) | — | |
| SCHEMBL6437698 | 0.77 | MGAM (0.43) | — | |
| SCHEMBL303947 | 0.77 | — | — | |
| SCHEMBL20058830 | 0.76 | ALDH1A1 (0.48) | — | |
| SCHEMBL28294538 | 0.76 | TSHR (0.41) | — | |
| SCHEMBL28294537 | 0.76 | NOS1 (0.36) | — | |
| SCHEMBL5792988 | 0.75 | MGAM (0.42) | — | |
| SCHEMBL4321838 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651286-A | A kind of highly selective 4-(4- aminophenyl) morpholine -3- ketone synthetic method | 新发药业有限公司 | 2019-04-19 | — | — | CN | claimed |
| CN-109651286-A | A kind of highly selective 4-(4- aminophenyl) morpholine -3- ketone synthetic method | 新发药业有限公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-106338781-B | The manufacture method of optical film | 柯尼卡美能达株式会社 | 2018-05-08 | — | — | CN | disclosed |